Submitted Jun 7 at 4:06
提交于 6 月 7 日 4:06

Question 1  问题 1
1 / 1 pts
1 / 1 分
Which one of the following is an example of a drug enzyme target?
以下哪一项是药物酶靶标的例子？

moclobemide binding to monoamine oxidase proteins
氨氯贝齐与单胺氧化酶蛋白结合
lignocaine binding to voltage-gated sodium channels
利多卡因与电压门控钠通道结合
reboxetine binding to noradrenaline transporter proteins
重新箱辛与去甲肾上腺素转运蛋白结合
nicotine binding to acetylcholine-gated sodium channels
尼古丁与乙酰胆碱门控钠通道结合
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Question 2  问题 2
0 / 1 pts
0 / 1 分
Activation of alpha1 adrenoceptors on sympathetic effectors leads to:
交感神经效应器上α1 肾上腺素受体的激活会导致：
Correct Answer  正确答案
constriction of vascular smooth muscle in skin, mucosa and abdominal viscera
皮肤、粘膜和腹腔内脏血管平滑肌收缩
relaxation of bronchial smooth muscle
支气管平滑肌松弛
decreased rate and force of cardiac muscle contraction
心肌收缩速率和力量降低
You Answered  您已回答
relaxation of gastrointestinal smooth muscle
胃肠道平滑肌松弛
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Question 3  问题 3
0 / 1 pts
0 / 1 分
The abscissa (horizontal axis) and ordinate (vertical axis) of agonist concentration-effect curves are best plotted with the following scales:
作用浓度-效应曲线的横坐标（水平轴）和纵坐标（垂直轴）最好用以下刻度绘制：
both axes logarithmic (log)
两个坐标轴都为对数刻度（log）
both axes linear  双轴线性
You Answered  您已回答

Correct Answer  正确答案
abscissa log; ordinate linear
横坐标对数；纵坐标线性

Question 4  问题 4
0 / 1 pts
0 / 1 分
Two agonists acting with opposing actions on the same tissue is a form of:
两种在相同组织上产生相反作用的激动剂是一种形式：
Correct Answer  正确答案
physiological antagonism
生理拮抗
You Answered  您的回答
chemical antagonism  化学拮抗
allosteric antagonism  调节性拮抗
irreversible antagonism  不可逆拮抗

Question 5  问题 5
0 / 1 pts
0 / 1 分
Regarding drug potency:  关于药物效力：
A drug that is more potent causes a specified effect at higher concentration Correct Answer
功效更强的药物在更高的浓度下产生指定效果 正确答案
It is a measure of the concentration of a drug that causes a specified effect You Answered
它是衡量药物引起指定效果所需浓度的指标 你回答了
It refers to the ability of the drug to bind to the target molecule
它指的是药物与靶分子结合的能力
It is measured as the KD
它被测量为 KD
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Question 6  问题 6
0 / 1 pts
0 / 1 分

The above figure shows a series of concentration-effect curves (A-D) to various agonists. Which agonist is the most potent, based on its concentration-effect curve?
上图显示了系列浓度-效应曲线（A-D）到各种激动剂。根据其浓度-效应曲线，哪种激动剂是最有效的？

You Answered  你回答了

Correct Answer  正确答案
Curve C  曲线 C
Curve D  曲线 D
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Question 7  问题 7
$0/1$$0/1$0//10 / 1 pts   $0/1$$0/1$0//10 / 1 分
Parasympathetic nervous system post-ganglionic fibres:
副交感神经节后纤维：
Correct Answer  正确答案
synapse on muscarinic receptors on the target tissues (effectors)
在靶组织（效应器）上的毒蕈碱受体上的突触
release choline as their neurotransmitter
作为它们的神经递质释放乙酰胆碱
You Answered  你回答了
release noradrenaline as their neurotransmitter
释放去甲肾上腺素作为它们的神经递质
synapse on nicotinic receptors on the target tissues (effectors)
在靶组织（效应器）上的烟碱受体上的突触

Question 8  问题 8
$0/1$$0/1$0//10 / 1 pts   $0/1$$0/1$0//10 / 1 分数
Sympathetic nervous system postganglionic fibres synapse on:
交感神经节后纤维在以下哪个部位发生突触：
Correct Answer  正确答案
$\alpha 1$$\alpha 1$alpha1\alpha 1 adrenoceptors in vascular smooth muscle
$\alpha 1$$\alpha 1$alpha1\alpha 1 在血管平滑肌上的肾上腺素受体
You Answered  你回答了
$\beta 1$$\beta 1$beta1\beta 1 adrenoceptors on bronchial smooth muscle
$\beta 1$$\beta 1$beta1\beta 1 支气管平滑肌上的肾上腺素受体
$\beta 2$$\beta 2$beta2\beta 2 adrenoceptors in the heart
$\beta 2$$\beta 2$beta2\beta 2 心脏中的肾上腺素受体
$\beta 1$$\beta 1$beta1\beta 1 adrenoceptors on gastrointestinal sphincters
$\beta 1$$\beta 1$beta1\beta 1 胃肠道括约肌上的肾上腺素受体