About LCGC International 关于 LCGC 国际
Founded in 1983, LCGC International is the leading provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally.
1983 年成立的 LCG 国际是分离科学市场领先的数字和印刷内容提供商，旨在全球范围内提升分离技术的生产力、效率以及整体价值。
With our commitment to editorial excellence, we have pioneered innovation across a broad portfolio of digital and print platforms.
凭借我们对编辑卓越的承诺，我们在广泛的数字和印刷平台上推动了创新。
Through our monthly print publication, website, newsletters, ebooks, webcasts, interviews, and special issues, which provide unbiased peer-reviewed articles, trusted troubleshooting advice, and best-practice applications solutions, LCGC International covers all key growth areas in the field of separation science. Laboratory-based analytical chemists and influential chromatographers can improve productivity and enhance their proficiency through LCGC International’s practical information, giving them a competitive advantage for the real-world challenges they face.
通过我们的月刊印刷出版物、网站、电子通讯、电子书、网络直播、访谈以及特别刊期，LCGC 国际涵盖了分离科学领域所有关键增长区域的无偏见同行评审文章、可信赖的故障排除建议和最佳实践应用解决方案。实验室分析化学家和有影响力的色谱学家可以通过 LCGC 国际的实际信息提高工作效率和增强专业技能，从而在他们面临的现实世界挑战中获得竞争优势。
Subscriptions 订阅
To subscribe to LCGC International, please see our subscriptions page:
要订阅 LCGC 国际版，请参阅我们的订阅页面：
https://one.chromatographyonline.com/subscribe/
To manage your subscription, please contact mmhinfo@mmhgroup.com
请联系我们 mmhinfo@mmhgroup.com 管理您的订阅。
Submit Press Releases to LCGCedit@mmhgroup.com
提交新闻稿至 LCGCedit@mmhgroup.com
LCGC Editorial Advisory Boards
LCGC 编辑顾问委员会
Marketing Opportunities 营销机会
A range of marketing options provide access to LCGC’s audience. Options include print and digital advertising, newsletter advertising, mail lists, webcasts, virtual events, video programs, content marketing, and custom programs
多种营销选项可接入 LCGC 的受众。选项包括印刷广告和数字广告、电子通讯广告、邮寄列表、网络直播、虚拟活动、视频节目、内容营销以及定制计划。
Learn More about Marketing Opportunities
了解更多的营销机会
Permissions 权限
For permissions to re-use figures or other content, please contact the Editorial Director, Caroline Hroncich, at chroncich@mjhlifesciences.com.
为了重新使用图表或其他内容，请联系编辑总监 Caroline Hroncich，邮箱地址为 chroncich@mjhlifesciences.com。
Fabrice Gritti 的马廷奖访谈
寡核苷酸的液相色谱替代模式
PFAS 和氟化化合物：考虑潜在的未来限制
柱上结构形成
稳健性与可再现性：是否存在能力危机？
未来展望和适用分离功率
寡核苷酸对映体的监管立场
讨论分析策略和 2DLC
可用的化学物质和产品对于 ASOs
分析反义寡核苷酸（ASOs）的挑战
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
质谱技术的新前沿：最大化离子利用
In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications.
在这个播客中，MOBILion Systems 的 CTO Daniel DeBord 描述了一种新的高分辨率质谱方法，该方法有望在组学应用中提高速度和灵敏度。
MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation.
MOBILion 最近引入了 PAMAF 运行模式，其中 PAMAF 代表平行积累与移动对齐的碎片化。
It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
它通过用高分辨率离子淌度替换四极杆的功能，大幅增加了用于质谱分析的离子比例。听听更多关于这一令人兴奋的新发展的内容。
Evaluating Dissolved Organic Matter with GPC and Spectroscopy
用 GPC 和光谱学评价溶解有机质
Gel permeation chromatography, three-dimensional excitation-emission matrix fluorescence spectroscopy, and UV-visible spectroscopy was utilized to assess road runoff passed through a filter filled with sludge from drinking water treatment plants to evaluate its capacity for removing dissolved organic matter (DOM).
使用凝胶渗透色谱、三维激发-发射矩阵荧光光谱和紫外-可见光谱来评估经过填有饮用水处理厂污泥滤料的路面径流，以评估其去除溶解有机物（DOM）的能力。
The Complexity of Oligonucleotide Separations
寡核苷酸分离的复杂性
Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules.
Peter Pellegrinelli，高级材料技术（AMT）的应用专家，解释了由于这些分子的独特化学性质，寡核苷酸分离的复杂性。
Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult.
不同的长度、序列复杂性和亲水疏水特性等问题使得有效的分离变得困难。
Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography.
分离科学家通过修改流动相组成、使用不同的离子对试剂，并探索如 HILIC 和离子交换色谱等替代分离模式来应对这些挑战。
Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability.
由于这些复杂性，AMT 引入了 HALO® Oligo 列柱，该列柱通过其创新的 Fused-Core® 技术和高 pH 稳定性提供了高分辨率和快速分离。
Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
彼得还解释了新列的内容，并展望了这些分离的未来以及接下来将会发生什么。
The LCGC Blog: Looking for Love in all the Wrong Mobile Phases
LCGC 博客：在所有错误的移动相中寻找爱情
In this edition of The LCGC Blog, Jonathan Shackman discusses what factors to consider when choosing a mobile phase for liquid chromatography (LC) procedures.
在本期《LCGC 博客》中，Jonathan Shackman 讨论了在选择液相色谱（LC）程序的流动相时需要考虑哪些因素。
Understanding the On-off Retention Mechanism of Oligonucleotides
理解寡核苷酸的开关保留机制
A team from the University of Geneva and Bayer AG present their findings on the on-off retention of oligonucleotides and the feasibility of separating them using very short columns.
来自日内瓦大学和拜耳 AG 的团队展示了他们在寡核苷酸的开关保留以及使用非常短的柱子分离它们的可能性方面的研究成果。
