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Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage
微纤维相关蛋白 4 的药物阻断可减少视网膜新生血管生成和血管渗漏
Anders Schlosser, Bartosz Pilecki, Claire Allen, Andrew V. Benest, Amy P. Lynch, Jing Hua, Nikita Ved, Zoe Blackley, Thomas L. Andersen, Dorle Hennig, Jonas
安德斯·施洛瑟、巴托什·皮莱茨基、克莱尔·艾伦、安德鲁·贝内斯特、艾米·林奇、晶华、尼基塔·维德、佐伊·布莱克利、托马斯·安徒生、多尔·亨尼格、乔纳斯

H. Graversen, Sören Möller, Sofie Skallerup, Maria Ormhøj, Clemens Lange, Hansjürgen T. Agostini, Jakob Grauslund, Steffen Heegaard, Ivanka Dacheva, Michael Koss, Wenzheng Hu, Bibiana Iglesias, Matthew S. Lawrence, Hans Christian Beck, Lasse Bach Steffensen, Nick S. Laursen, Gregers R. Andersen, Uffe Holmskov, David O. Bates, Grith L. Sorensen
H. Graversen, Sören Möller, Sofie Skallerup, Maria Ormhøj, Clemens Lange, Hansjürgen T. Agostini, Jakob Grauslund, Steffen Heegaard, Ivanka Dacheva, Michael Koss, Wenzheng 胡, Bibiana Iglesias, Matthew S. Lawrence, Hans Christian Beck, Lasse Bach Steffensen, Nick S. Laursen, Gregers R. Andersen, Uffe Holmskov, David O. Bates, Grith L. Sorensen
PII: S1525-0016(25)00042-5
PII:S1525-0016(25)00042-5

DOI: https://doi.org/10.1016/j.ymthe.2025.01.038
DOI: https://doi.org/10.1016/j.ymthe.2025.01.038

Reference: YMTHE 6752  型号: YMTHE 6752
To appear in: Molecular Therapy
出现在: 分子疗法
Received Date: 23 August 2024
收稿日期: 2024-08-23

Accepted Date: 22 January 2025
录用日期: 2025-1-22
Please cite this article as: Schlosser A, Pilecki B, Allen C, Benest AV, Lynch AP, Hua J, Ved N, Blackley Z, Andersen TL, Hennig D, Graversen JH, Möller S, Skallerup S, Ormhøj M, Lange C, Agostini HT, Grauslund J, Heegaard S, Dacheva I, Koss M, Hu W, Iglesias B, Lawrence MS, Beck HC, Steffensen LB, Laursen NS, Andersen GR, Holmskov U, Bates DO, Sorensen GL, Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage, Molecular Therapy (2025), doi: https://doi.org/10.1016/j.ymthe.2025.01.038.
请引用本文为: Schlosser A, Pilecki B, Allen C, Benest AV, Lynch AP, 华 J, 维德 N, 布莱克利 Z, 安德森 TL, 亨尼格 D, 格拉弗森 JH, 穆勒 S, 斯卡勒普 S, 奥姆霍伊 M, 兰格 C, 阿戈斯蒂尼 HT, 格劳斯伦德 J, 希高德 S, 达切娃 I, 科斯 M, 胡 W, 伊格莱西亚斯 B, 劳伦斯 MS, 贝克 HC, 斯蒂芬森 LB, 劳森 NS, Andersen GR、Holmskov U、Bates DO、Sorensen GL,微纤维相关蛋白 4 的药理学阻断可减少视网膜新血管生成和血管渗漏,分子治疗 (2025),doi:https://doi.org/10.1016/j.ymthe.2025.01.038
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© 2025 The Author(s). Published by Elsevier Inc. on behalf of The American Society of Gene and Cell Therapy.
© 2025 作者。由 Elsevier Inc. 代表美国基因与细胞治疗学会出版。

Endothelial interaction with ECM causes vascular leakage
内皮与 ECM 的相互作用导致血管渗漏

Blocking ECM reduces vascular leakage
阻断 ECM 可减少血管渗漏

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