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HKU Clinical Trials Centre 香港大學臨床試驗中心
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【研究結果公佈🎉】 生物製劑一期數據理想 嚴重哮喘病人現曙光
感謝各位志願者曾在2019年參與由香港大學臨床試驗中心舉辦之哮喘藥研究 (CTC1843)。很榮幸告知大家該藥物之三期研究數據已呈交至中國藥監局提交藥物註册申請， 現正等待審批。如獲批准使用，將為嚴重哮喘病人帶來希望。
*****
研究背景及結果摘要:
在嚴重哮喘患者中，超過80%患者體內帶有一種名為「嗜酸性粒細胞」的免疫系統白血球，研究發現針對嗜酸性粒細胞的生物製劑能有效治療此類嚴重哮喘，而Benralizumab便是此類生物製劑之一。此藥屬於單株抗體藥物，能直接及迅速地消耗大部分嗜酸性和嗜鹼性白血球，從而減輕病情惡化，並可減少使用口服皮質類固醇、改善肺功能及生活質素。Benralizumab已在超過70個國家註冊使用，包括美國、歐盟、日本和南韓等，然而其有效性及安全性並未於中國人身上進行評估。
研究團隊於早前在瑪麗醫院共招募了36名華裔健康志願者，接受一次Benralizumab皮下注射，是次一期臨床試驗結果為國內開展的Benralizumab三期試驗提供支持: 其研究對象為患有不受控嚴重哮喘、並正在服用吸入型皮質類固醇和長效 β2 促效劑的亞洲(主要是中國)病人，以評估其有效性及安全性是否與西方人相近。藥廠已就所得之三期研究數據向中國藥監局提交藥物註册申請， 現正等待審批。是次臨床研究結果已於學術期刊 Dovepress發表，詳情可參閱:
https://doi.org/10.2147/DDDT.S392155
*****
全賴各位志願者熱心參與臨床研究，才得以推動哮喘藥物的研發，從而幫助有需要的病人。我們再次代表研究團隊向各位衷心致謝。
===================================
【📝登記成為臨床試驗研究志願者，第一時間接收我哋最新嘅研究同埋招募資訊】
📍網站: https://public.hkuctc.com/tc/joinus
【🛎追蹤我哋嘅 Facebook同Instagram專頁，接收更多我哋嘅最新資訊】
📍Facebook: HKU Clinical Trials Centre 香港大學臨床試驗中心 |
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📍Instagram: HKUCTC | https://www.instagram.com/hkuctc/
====================================
#香港大學臨床試驗中心 #HKUCTC #一期臨床試驗 #Phase1ClinicalTrials #哮喘 #Asthma #Benralizumab #CTC1843
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【研究結果公佈
】 生物製劑一期數據理想 嚴重哮喘病人現曙光
】 生物製劑一期數據理想 嚴重哮喘病人現曙光感謝各位志願者曾在2019年參與由香港大學臨床試驗中心舉辦之哮喘藥研究 (CTC1843)。很榮幸告知大家該藥物之三期研究數據已呈交至中國藥監局提交藥物註册申請， 現正等待審批。如獲批准使用，將為嚴重哮喘病人帶來希望。
*****
研究背景及結果摘要:…
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【臨床試驗專欄文章「乙肝藥物臨床試驗」】
am730「醫理」專欄的第三篇臨床試驗文章「乙肝藥物臨床試驗」由港大醫學院臨床醫學學院內科學系副主任、肝腸胃科講座教授及臨床教授李樹芬醫學基金會基金教授(內科)袁孟峰教授撰寫，向大家講解乙型肝炎的最新治療方向。想要了解更多詳情，請點擊以下連結
：
：「醫…
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過去25年，港大臨床試驗中心一直同香港並肩同行，邁步向前。為咗慶祝呢個重要嘅里程碑，中心舉辦咗「銀禧慶典及慶祝晚宴」，邀請咗政府、學術界以及業界嘅代表，仲有勞苦功高為臨床研究貢獻嘅一眾同事參加，約300人歡聚一堂，場面非常熱鬧
。席上首先由港大臨床試驗中心首席總監梁偉強教授致辭歡迎所有嘉賓蒞臨出席晚宴，並對中心過去喺臨床試驗工作嘅努力予以肯定。之後有香港大學署理校長王於漸教授、特首政策小組組長黃元山博士、以及醫院管理局主席范鴻齡先生致辭，佢哋表揚中心對促進香港醫療創科發展嘅貢獻，致力為社會謀福祉。
。席上首先由港大臨床試驗中心首席總監梁偉強教授致辭歡迎所有嘉賓蒞臨出席晚宴，並對中心過去喺臨床試驗工作嘅努力予以肯定。之後有香港大學署理校長王於漸教授、特首政策小組組長黃元山博士、以及醫院管理局主席范鴻齡先生致辭，佢哋表揚中心對促進香港醫療創科發展嘅貢獻，致力為社會謀福祉。適逢銀禧之慶，當晚同時舉行咗兩個簡單而隆重嘅典禮。先有長期服務獎頒獎典禮，向10位在服務了中心5至20年的同事頒發長期服務獎
，答謝佢哋多年嚟全心全意為中心發展而努力；後有臨床研究見習生計劃2022-23畢業典禮
，5位見習生完成咗為期一年嘅訓練。佢哋到過三個部門，喺唔同崗位邊學邊做，亦同大家分享咗佢哋嘅得著同感受。而家就等我哋睇睇當晚嘅精彩時刻啦！
，答謝佢哋多年嚟全心全意為中心發展而努力；後有臨床研究見習生計劃2022-23畢業典禮，5位見習生完成咗為期一年嘅訓練。佢哋到過三個部門，喺唔同崗位邊學邊做，亦同大家分享咗佢哋嘅得著同感受。而家就等我哋睇睇當晚嘅精彩時刻啦！
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【臨床試驗專欄文章「一期臨床試驗——從實驗到臨床」】am730「醫理」專欄的臨床試驗第二篇文章「一期臨床試驗——從實驗到臨床」由HKU-CTC一期中心醫學總監葉逸軒教授執筆，向各位講解為什麼一期臨床試驗是將基礎研究發現轉化為臨床實際應用的重要橋樑。想要了解更多，請點擊以下連結：
：請…
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【HKU-CTC藥物小百科 為什麼每年都需要接種流感疫苗？
】
為什麼每年都需要接種流感疫苗？】政府每年都鼓勵市民接種季節性流感（流感）疫苗，以應對流感高峰期。為什麼我們每年都需要接種流感疫苗呢？
流感病毒表面的抗原容易發生變化，導致病毒產生變異 ，流行的病毒株亦可能不斷改變 。世界衞生組織（世衞）每年會就北半球和南半球這兩個地區分別召開會議，預測下一個流感季節流行的病毒株，並提出流感疫苗的病毒成分的建議 。流感疫苗的成分每年都會根據流行的病毒株進行更新，以增強疫苗的有效性 。因此，今年流感疫苗的成分有機會與去年不同，每年接種更新的疫苗才能有效預防該年度的流感。此外，上一年度接種疫苗時建立的免疫力會隨時間減弱。每年接種流感疫苗有助於確保身體產生足夠抗體，達至保護作用的水平 。…
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